Expresión de búsqueda:
CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4
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DeCS
Descriptor
Inglés
:
Cyclic Nucleotide Phosphodiesterases, Type 4
Descriptor
Español
:
Fosfodiesterasas de Nucleótidos Cíclicos Tipo 4
Descriptor
Portugués
:
Nucleotídeo Cíclico Fosfodiesterase do Tipo 4
Categoría:
D08.811.277.352.640.150.400
D12.644.360.008.400
D12.776.476.008.400
Definición
Inglés
:
A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory
cells
and may play a
role
in the regulation of CELL-MEDIATED
IMMUNITY
. The enzyme
family
includes over twenty different variants that occur due to multiple
ALTERNATIVE SPLICING
of the mRNA of at least four different
genes.
Combinados
Inglés
:
Cyclic Nucleotide Phosphodiesterases, Type 4
/
antagonists & inhibitors
use
Phosphodiesterase 4 Inhibitors
Nota Histórica
Inglés
:
2008(1981)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52679
Identificador Único:
D054703
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS